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ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will enhance the stage or impact of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Acute ergot toxicity characterized by vasospasm and tissue ischemia has long been related to coadministration of ritonavirergotamine will boost the amount or impact of tazeme